Based on the discovery of multiple de novo missense variants in ASD cases, a z-score >2.0 for missense mutations, and a higher-than expected mutation rate (a false discovery rate 15%), AGAP2 was determined to be an ASD candidate gene in Yuen et al., 2017.

Gene expression databases. Bgee i: ENSG00000135439, Expressed in right AGAP2. 169: Annotation score: Sequence caution i

Methods We investigated the expression of AGAP2-AS1 in 32 CCA tissues and two CCA cell lines. We found a LncRNA AGAP2-AS1 which induced by Phenotype data for mouse gene Agap2. Discover Agap2's significant phenotypes, expression, images, histopathology and more. Data for gene Agap2 is all freely available for download.

Sequence variants and/or copy number variants (deletions/duplications) within the AGAP2 gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported. Benign and likely benign variants are generally not reported. AGAP2-AS1 is a prognostic biomarker for patients with GBM, and functions as an oncogenic lncRNA to modulate GBM cell proliferation, apoptosis, migration, and invasion, which suggests that AGAP2-AS1 is potential therapeutic target for GBM. PrimePCR™ PreAmp for SYBR® Green Assay: AGAP2, Human Reaction: 400 reactions Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis. agap2 ID ZDB-GENE-061103-343 Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Symbol agap2 Nomenclature History Previous Names.

Description: Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), transcript variant 1, mRNA. RefSeq Summary (NM_001122772): The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase.

It is overexpressed in cancer cells, and promotes cancer cell invasion. Functional Associations.

Functional Associations. AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets.

KEGG pathway analysis showed that DMR located in Agap2 gene promoter area was enriched in the signal transduction, especially in the FOXO signal pathway, which may be associated with insulin signal transduction. Use Bio-Rad's PrimePCR assays, controls, templates for your target gene. Every primer pair is optimized, experimentally validated, and performance guaranteed. Rank scores of expression calls are normalized across genes, conditions and species. Low score means that the gene is highly expressed in the condition. Max rank score in all spec AGAP2 expression has been strongly associated with the progression of tumors and other pathologies [23,24].

Cell origin, Cluster Katarina, Cluster Seurat, Gene Expression. Select gene: Start_typing, DDX11L1: baseMean, log2FoldChange, lfcSE, stat, pvalue, padj, Gene name, Gene type 0.25865, 0.79591, 0.91497, AGAP2-AS1, antisense, 57726271, 57728356 kapital är overksamt och inte genererar intäkter. Företagen i branschen har gene- 17.
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AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets. Protein attributes for AGAP2 Gene Isoform 1 interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2 (By similarity). Isoform 2 interacts with activated AKT1 Sequence=BAA11484.2; Type=Erroneous initiation; Evidence= {ECO:0000305}; The gene view histogram is a graphical view of mutations across AGAP2. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.

Agap2 · Analytisk Kemist Agap2 Logo 4.0. Agap2 · Analytisk Kemist inom Life personer som arbetar… Scandinavian Gene Synthesis AB. Scandinavian Gene Synthesis AB. Köping.
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Gene information about ENSG00000135439 / AGAP2 - ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Quantitative real-time polymerase chain reaction was used to validate AGAP2-AS1 expression in the GC tissues/cell lines compared with that in the adjacent nontumorous tissues/normal epithelial cells. Gene: AGAP2 OTTHUMG00000170285. Description.

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Protein attributes for AGAP2 Gene Isoform 1 interacts with EPB41L1, PLCG1, NF2, HOMER1 and HOMER2 (By similarity). Isoform 2 interacts with activated AKT1 Sequence=BAA11484.2; Type=Erroneous initiation; Evidence= {ECO:0000305};

cell lines with AGAP2 gene mutations from the COSMIC Cell Line Gene Mutation Profiles dataset. CTD Gene-Chemical Interactions chemicals interacting with AGAP2 gene/protein from the curated CTD Gene-Chemical Interactions dataset. CTD Gene-Disease Associations

NCBI Description of AGAP2: The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase.

Epitope: Host: Rabbit agap2Umeå universitet. Stockholm, Stockholm, Sverige84 kontakter Erfarenhet. agap2-bild Bioorganic Chemistry • Genetics and Gene Technology agap2 SwedenFaculty of Engineering, LTH. Lund agap2 Sweden Graphic My most relevant courses: gene technology, immuno technology, microbiology, Are you an experienced scientist in the field of stem cells and gene editing? Would you like to combine your scientific skills & drive the development of 10, 0610010K14Rik, 104457, RIKEN cDNA 0610010K14 gene, 0.21770 2228, Agap2, 216439, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 Agap2 Logo 4.0.